Manchester United will travel to Portman Road to face Ipswich Town in the Premier League today.
It will be the first time Ruben Amorim takes charge of Man United as their new manager.
He has a few tricky decisions to make as United are expected to line up in a 3-4-2-1 formation.
Amorim is keen on deploying a three-player defensive set-up but faces a massive challenge with injuries depleting his options.
Matthijs de Ligt and Jonny Evans are expected to be guaranteed starters, but there are question marks on who will play alongside them.
Harry Maguire has been injured for a few weeks and Victor Lindelof limped off during Sweden’s Nations League clash with Slovakia.
Leny Yoro has trained over the past week. However, United are yet to confirm if the £52m summer signing has completed his recovery from a foot injury he suffered in pre-season.
The defensive puzzle remains unsolved as Amorim prepares for his debut match.
Lisandro Martinez could start on the left side of the back three if Yoro remains unavailable.
There are doubts over the Argentina international after he withdrew from international duty with a back issue.
Despite not being fit, he will be eager to start in Amorim’s first game.
United fans will be hoping that the two-week break has allowed him enough time to recover.
If he is not fit to start, the Portuguese manager could be forced to use Casemiro as an emergency centre-back.
He could take the central slot in the back three and help United play out from the back.
He is no stranger to this role, having filled in at the heart of defence seven times under manager Erik ten Hag last season when injuries plagued United’s backline.
Stats from Transfermarkt.com.